台耳醫誌

雜誌專區 -第59卷第2期

原著 
Bilaterality and Multifocality in Warthin's Tumor: Implications in Surgery Extent  僅供有效會員 登入會員查看全文
69~76 
英文 
Warthin’s tumor、bilaterality、multifocality 
Ting-Shiuan Yeh1 、Chi-Kuang Young2,3 、Chun-Ta Liao2,4 、Chung-Jan Kang2,4 、Shiang-Fu Huang2,4,5  
Department of Otolaryngology, Head and Neck Surgery, New Taipei Municipal Tucheng Hospital1 、Medical college, Chang Gung University2 、Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial,Keelung branch, Keelung3 、Department of Otolaryngology, Head and Neck Surgery, Chang Gung Memorial, Linkou4 、Graduate Institute of Clinical Medical Sciences, Chang Gung University5  
BACKGROUND: Warthin's tumor (WT) is the second most common benign parotid gland tumor and is often associated with smoking. The optimal surgical approach for WT remains controversial, with some clinicians even advocating for observation alone. Bilaterality and multifocality are notable characteristics of WT that affect management decisions.
METHODS: A retrospective analysis was conducted on parotidectomy performed for WT during 2004-2023. Data on demographics, smoking history, alcohol consumption, and areca quid chewing were collected. The effects of bilaterality and multifocality on tumor recurrence were assessed, and risk factors for bilaterality were explored.
RESULTS: Of 854 patients, 235 had WT neoplasms, with 26% of them harboring bilateral tumors. The multifocality of tumors was strongly associated with areca quid chewing (p = 0.014) but not with smoking or alcohol consumption. Multiple nodularity was strongly associated with bilateral WT (p < 0.001). The recurrence rate, which was 4.2% after superficial parotidectomy, was also associated with the bilaterality of WT (p < 0.001).
CONCLUSION: This study suggests that parotidectomy is the treatment of choice for WT with multiple nodules. Recurring tumors following the excision of WT neoplasms are likely second tumors rather than true recurrences. Patients with multiple nodules must be regularly followed up because they carry a high risk of bilateral WT.
(J Taiwan Otolaryngol Head Neck Surg 2024; 59:69-76)