Oral cancer stands as one of the most prevalent head and neck cancers worldwide. The standard primary management of oral cancer involves surgical resection with a safety margin, accompanied by optional neck dissection and postoperative adjuvant therapies such as radiation or chemoradiation. The surgical approach and techniques employed vary according to the anatomical structures and locations within the oral cavity. In this case, we presented a 60-year-old man diagnosed with right mouth angle squamous cell carcinoma, with extensions to the upper and lower lips, the inner buccal mucosa and the skin of face. Following wide excision performed with safety margins, we employed a scarcely used technique, the double rhomboid flap reconstruction to address the mouth angle defect. The nasogastric tube was removed on postoperative day 15, and the patient resumed an oral diet smoothly. Throughout the 3-month follow-up period, the wound and flap over the right mouth angle exhibited healthy healing and cleanness, and the patient reported no issues of saliva drooling or choking episodes during oral intake. (J Taiwan Otolaryngol Head Neck Surg 2023; 58:177-182)
