台耳醫誌

Rosai-Dorfman disease is a rare disorder with a prevalence of 1 : 200,000. Most patients present with bilateral, massive and painless cervical lymphadenopathy, while extranodal involvement has been reported in 43% cases. There is no ideal protocol for the treatment, and multiple strategies of therapy have been used with varying success, including observation, surgery, corticosteroids, chemotherapy, radiotherapy and immunomodulatory therapy. We presented a case of a 49-year-old woman with Rosai-Dorfman disease presenting as unilateral neck masses, treated with surgical excision with no local recurrence noted 6 months postoperatively. Due to its rarity, alternating symptoms and various treatment strategies, we reported this case and reviewed the relevant literature regarding the diagnosis and treatment. We aimed at highlighting the importance of a thorough evaluation for neck masses, which might be a sign of Rosai-Dorfman disease requiring further systemic survey.
(J Taiwan Otolaryngol Head Neck Surg 2021; 56:197-201)