台耳醫誌

Schwannoma is the most common nerve sheath tumor, and it is composed of Schwann cells. However, nasal septal schwannomas are rare, with only 34 benign cases reported in the literature. We reported the case of a 63-year-old man who had a right nasal obstruction for more than 1 year. The patient denied symptoms of epistaxis, smelling a foul odor, anosmia, headache, or a history of nasal trauma. Anterior rhinoscopy revealed a tumor on the right nasal septum with a wide-based attachment, sized 1.5 × 1 × 1 cm. Excision with the assistance of a nasal speculum under general anesthesia was performed. Histopathology showed spindle cells with alternating hypercellular areas (Antoni A area), hypocellular areas (Antoni B area) and focal nuclear palisading (Verocay body). Immunohistochemistry revealed that the tumor cells were diffusely positive for S-100 and negative for CD34. Pathology confirmed the diagnosis of schwannoma. There was no recurrence during the follow-up period of one year.
(J Taiwan Otolaryngol Head Neck Surg 2021; 56:119-123)