台耳醫誌

Sarcomatoid carcinoma (SC) is a rare, but highly malignant, variant of squamous cell carcinoma (SCC) characterized by dysplastic epithelial and stromal elements with invasive spindle cells. It accounts for about 1% to 4% of all SCCs with male predominance and an incidence peak in the sixth and seventh decades of life. The development of SC is associated with alcohol use, tobacco use, and previous radiotherapy. Here, we present a rare case of SC arising from the oropharynx in a 70-year-old male presenting with globus sensation and odynophagia. This patient was successfully managed with excision and radiotherapy over a 1-year follow-up period.
(J Taiwan Otolaryngol Head Neck Surg 2021; 56:47-51)